European
Ln Faculty Lectures (L1-L19)
Wn Interactive Workshops, Seminars and Special Presentations (W1-W10)
Sn Scholars’ Oral Presentations (S1-S31)
Sunday, 10 June |
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| 11:00-18:00 | Arrival of Scholars and Faculty at the Certosa di Pontignano Assignment to rooms in the hotel wing of the Certosa. All food during the week will be provided by the restaurant of the Certosa (breakfast, lunch and dinner). |
| 15:30-16:30 | A short guided tour through the Certosa, its Chapel, Cloisters and Garden |
| 17:30-19:00 | Opening Ceremony |
L1 Welcome The European Pain School 2018 Greetings from the University of Siena Grünenthal Scientific Relations Management, Aachen, Germany Pain: a new scientific discipline About the IASP and how you can participate The Certosa di Pontignano and its history Monasteries, medieval forerunners of Universities and Hospitals Scholars’ self-introduction |
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| 20:30 | Wine reception followed by dinner, then leisure time |
Monday, 11 June |
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| Opening remarks Bill Maixner, Durham, NC, USA |
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| 9:00-10:00 | L2 The pain system: fundamentals of pain processing in the PNS and CNS Jordi Serra (Barcelona, Spain) |
| 10:00-10:15 | S1 Does spinal glia activation involve in chemotherapy induced neuropathic pain? Duygu Krings (Aachen, Germany) |
| 10:15-10:30 | S2 Pain specific local anesthesia without neurotoxicity Yishai Kushnir (Jerusalem, Israel) |
| 10:30-11:00 | Coffee break |
| 11:00-11:15 | S3 Investigating the role of prokineticin system in a murine model of chemotherapy-induced peripheral neuropathy Giorgia Moschetti (Milan, Italy) |
| 11:15-11:30 | S4 Effect of short-term noxious heat stimulation on human experimental models of itch Daniele Riccio (Aalborg, Denmark) |
| 11:30-12:30 | L3 Neural plasticity: hyperexcitability in neurons and neuronal networks as a generator of chronic pain Marshall Devor (Jerusalem, Israel) |
| 13:00-15:00 | Lunch break |
| 15:00-16:00 | L4 The role of PNS drive in CNS sensitisation of chronic pain patients Lars Arendt-Nielsen (Aalborg, Denmark) |
| 16:00-16:15 | S5 Age-related dysfunction in endogenous pain inhibition and its association with cognitive inhibition and changes in frontal brain areas Stefanie Bunk (Groningen, The Netherlands) |
| 16:15-16:30 | S6 Project Plan: morphological and functional brain alterations in fibromyalgia patients Hans-Christoph Aster (Würzburg, Germany) |
| 16:30-17:00 | Coffee break |
| 17:00-17:15 | S7 Does anxiety enlarge reflex receptive fields? Edward Lannon (Tulsa, OK, USA) |
| 17:15-17:30 | S8 Task-dependent cortical reorganization in sensorimotor body representations in amputees — impact on current theories of phantom pain Christopher Milde (Mannehim, Germany) |
| 17:30-18:30 | L5 Pain in dementia Miriam Kunz (Groningen, The Netherlands) |
| 20:00-21:30 | Dinner in the small Cloister |
| 21:30 | W1 Behavioral tests & tools in pain research, a hands-on presentation of equipment for experimental pain research Federico Oggioni (Ugo Basile Srl. Gemonio, Varese, Italy) |
Tuesday, 12 June |
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| 9:00-10:00 | L6 Unraveling the mysteries of complex persistent pain conditions Bill Maixner (Durham, NC, USA) |
| 10:00-10:15 | S9 Analgesic and neuroprotective effect of bromelain in sciatic nerve ligated model of neuropathic pain in Wistar rats Ahmed Bakare (Ilorin, Nigeria) |
| 10:15-10:30 | S10 Central neuropathic pain in multiple sclerosis is associated with widespread damage of pain processing and modulation pathways Michal Rivel (Tel Aviv, Israel) |
| 10:30-11:00 | Coffee break |
| 11:00-11:15 | S11 Peripheral and central nervous contributions to changes in heat pain perception during repetitive laser stimulation in healthy subjects Daniela Rosenberger (Mannheim, Germany) |
| 11:15-11:30 | S12 Spatially distributed injections of NGF induces enlarged area of pain and prolonged muscle hypersensitivity Line Sørensen (Aalborg, Denmark) |
| 11:30-12:30 | L7 Role of melatonin in pain modulation Giancarlo Carli (Siena, Italy) |
| 13:00-15:00 | Lunch break |
| 15:00-16:00 | L8 Can the facial expression of pain substitute the self-report of pain? Miriam Kunz (Groningen, The Netherlands) |
| 16:00-16:15 | S13 Self-management interventions for women with cardiac pain: a systematic review and meta-analysis Ann Bjørnnes (Toronto, ON, Canada) |
| 16:15-16:30 | S14 Resting-state fMRI functional connectivity within cortico-limbic networks is linked to the individual magnitude of emotional pain modulation Norma Rosenek (Reading, UK) |
| 16:30-17:00 | Coffee break |
| 17:00-17:15 | S15 The efficacy of postoperative pain management in total hip arthroplasty Jolanta Sułek (Krakow, Poland) |
| 17:15-17:30 | S16 Investigating the impact of visual experience on the perception of nociceptive stimuli in normally sighted and visually deprived people Camille Vanderclausen (Brussels, Belgium) |
| 17:30-18:30 | L9 The efficacy of psychological approaches in acute and chronic paediatric pain Christina Liossi (Southampton, UK) |
| 20:00-21:30 | Dinner in the small Cloister |
| 21:30 | W2 Organization of debate teams |
Wednesday, 13 June |
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| 9:00-10:00 | L10 Measuring and modulating infant pain Rebeccah Slater (Oxford, UK) |
| 10:00-10:15 | S17 What’s up Doc? Treating children in chronic pain. Why medicine should think less doctor, more storyteller Mary Lockwood (Manchester, UK) |
| 10:15-10:30 | S18 Morphological and functional changes in the nociceptive system in rat models of diabetic peripheral neuropathy – contribution of TRP channels? Bastian Schlickenrieder (Mannheim, Germany) |
| 10:30-11:00 | Coffee break |
| 11:00-11:15 | S19 Intensive interdisciplinary pain treatment for pediatric chronic headache: examining improvements in physical function and participation Julie Shulman (Boston, MA, USA) |
| 11:15-11:30 | S20 Scorpion α-toxins affect intracellular signaling in primary sensory neurons via TTX-sensitive voltage gated sodium channels Marianne Van Cann (Cologne, Germany) |
| 11:30-12:30 | L11 Assessing the pain code by intraneural recording in humans Jordi Serra (Barcelona, Spain) |
| 13:00-15:00 | Lunch break |
| 15:00-16:00 | L12 Methodologies in clinical assessment of pain phenotypes: biopsychosocial factors Bill Maixner (Durham, NC, USA) |
| 16:00-16:15 | S21 Why do analgesic clinical trials fail? Raheleh Heidari (Feidt) (Basel, Switzerland) |
| 16:15-16:30 | S22 EEG signature of systemilycsystemic induced anesthesia vs induction via the mesopontine tegmental anesthesia area (MPTA) Tamir Avigdor (Jerusalem, Israel) |
| 16:30-16:45 | S23 Pain-free surgery: anesthesia-like state induction and maintenance by focal activation of extra-synaptic GABAA receptors, but not glycine receptors Mark Baron (Jerusalem, Israel) |
| 16:45-17:15 | Coffee break |
| 17:15-18:15 | L13 Pain and consciousness Marshall Devor (Jerusalem, Israel) |
| 20:00-21:30 | Dinner in the small Cloister |
| 21:30 | W3 EPS 2018 Neuropathic Pain Quiz!! Jordi Serra (Moderator) |
| Stargazing night... with Prof. Vincenzo Millucci |
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Thursday, 14 June |
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| 9:00-10:00 | L14 The postnatal development of spinal sensory circuits Stephanie Koch (London, UK) |
| 10:00-10:30 | W4 Duetto on pain-sensation and suffering Marshall Devor (Moderator) a) Topic: “When is pain tolerance shaped more, in infancy or the school years” Faculty: Christina Liossi and Rebeccah Slater |
| 10:30-11:00 | Coffee break |
| 11:00-11:30 | W4 Duetto on pain-sensation and suffering
Marshall Devor (Moderator) b) Topic: "How can we tell if pain originates in the PNS or CNS?” Faculty: Jordi Serra and Stephanie Koch |
| 11:30-12:30 | L15 The development of pain perception in early life Rebeccah Slater (Oxford, UK) |
| 13:00-15:00 | Lunch break |
| Afternoon and Evening: Excursion to Siena old town | |
| 15:00-18:00 | Guided tour to historical Siena, visit of the Cathedral and City Hall and to a 'Contrada' Museum |
| 19:00-20:00 | Aperitif in Piazza del Campo |
| 20:00-24:00 | Free time for Scholars in Siena / Faculty Dinner (plan to return to the Certosa on your own) |
Friday, 15 June |
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| 9:00-10:00 | L16 Neuroinflammation and pain Jürgen Sandkühler (Vienna, Austria) |
| 10:00-10:15 | S24 Axonal GABAA modulates C-fibres excitability and mediates neuron-glia cross talk via allopregnanolone Veronica Bonalume (Milan, Italy) |
| 10:15-10:30 | S25 Beyond evoked endpoints? Sleep, cognition and motivation in rat models of chronic inflammatory pain Gary Gilmour (Windlesham, UK) |
| 10:30-11:00 | Coffee break |
| 11:00-11:15 | S26 Disinhibition of spinal cord pain pathways underlies neuropathic pain hypersensitivity in rodents of both sexes Josiane Mapplebeck (Toronto, ON, Canada) |
| 11:15-11:30 | S27 Involvement of AT2R and HCN2 ion channels in inflammatory pain hypersensitivity in mice Larissa Garcia Pinto (London, UK) |
| 11:30-12:30 | L17 The Marsili syndrom Anna Maria Aloisi (Siena, Italy) |
| 13:00-15:00 | Lunch break |
| 15:00-16:00 | L18 Spinal inhibition of touch Stephanie Koch (London, UK) |
| 16:00-16:15 | S28 Effects of methylglyoxal, glyoxal and 3-DG on cutaneous nociceptors: mechanisms of sensitization, excitation or desensitization Anna Becker (Erlangen, Germany) |
| 16:15-16:30 | S29 Divergent modulation of nociception by glutamatergic and GABAergic neuronal subpopulations in the periaqueductal gray Jose Grajales-Reyes (St. Louis, MO, USA) |
| 16:30-17:00 | Coffee break |
| 17:00-17:15 | S30 Trends in tramadol Kate Liu (Aachen, Germany) |
| 17:15-17:30 | S31 Adherence to prophylaxis pharmacotherapies in patients with Medication Overuse Headache: a 10-year experience in a single-centre Lanfranco Pellesi (Modena, Italy) |
| 17:30-18:30 | L19 Central pain amplifier Jürgen Sandkühler (Vienna, Austria) |
| 20:00-21:30 | Dinner in the small Cloister |
| 21:30 | W6 Experiments in the pain laboratory – sensory dissociation during limb ischemia Jordi Serra (Barcelona, Spain) |
Saturday, 16 June |
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| 9:00-10:00 | W7 Ethical considerations and limitations of pain research and treatment in humans and animals Manfred Zimmermann (Heidelberg, Germany) 20 min presentation followed by a panel discussion of specific ethical issues, with: Manfred Zimmerman, Jordi Serra, Marshall Devor and Faculty |
| 10:00-10:30 | W8 Scholars’ controversial debates on the following topics Marshall Devor and Jordi Serra (Moderators) a) Resolved: “Intense focal pain is worse than diffuse widespread pain” |
| 10:30-11:00 | Coffee break |
| 11:00-11:30 | W8 Scholars’ controversial debates on the following topics Marshall Devor and Jordi Serra (Moderators) b) Resolved: “Late sensory changes following early trauma is adaptive for the child later in life” |
| 11:30-12:00 | W9 Open Forum - Pain Science and Medicine: how have we been doing? Neural mechanisms Old drugs, new drugs Procedures and surgery Organizing concepts (not a symptom, bio-psychosocial, not just medical) Discussants: Marshall Devor, Jordi Serra, Jürgen Sandkühler, Christina Liossi, Bill Maixner |
| 12:00-12:30 | W10 Evaluation of EPS 2018 by Scholars and Faculty, parting words - General discussion of the EPS experience and suggestions on how to modify/improve EPS in the future - Parting words from Anna Maria Aloisi and Bill Maixner |
| 13:00-15:00 | Lunch break |
| 16:00 | Departure to Terme Antica Querciolaia, Rapolano Terme Spa, Dinner and Live Music |
| 00:00 | Return to the Certosa |
Sunday, 17 June |
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| Departure from the Certosa di Pontignano Goodbyes! |
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